TESTOPEL (Testosterone Pellet Therapy)

TESTOPEL is FDA approved for testosterone deficiency in men. In lower doses it is used “off-label” in women for low libido, menopausal symptoms, and fatigue.


TESTOPEL is a testosterone pellet (about the size of a tic tac) that is inserted underneath the skin, below the belt line. The pellet provides a slow, steady release of testosterone over 3 to 5 months. Once the pellet is inserted it cannot be removed.


  • Sleep
  • Mood
  • Libido
  • Lean Muscle Mass
  • Increased Bone Density
  • Decreased Joint Discomfort
  • Menopause Symptoms
  • Hot flashes
  • Energy

Frequently Asked Questions

1. Is TESTOPEL covered by insurance?

Possibly, but it depends on your insurance. For men, we can obtain a prior authorization through the drug company. For women, the procedure may be subject to your deductible. Note: If you have Coventry, a prior authorization is required.

2. What is the cost?

The cost is $82 per pellet and $205 for the insertion. We request  a partial payment of $50 per pellet after the insertion

3. Does the procedure hurt?

Patients report minimal discomfort. After the anesthetic has been injected, you should not feel anything. Some patients reports bruising and mild discomfort one week after the procedure. That is why it is important to apply an ice pack when you get home.

4. Should I continue other methods of testosterone replacement?

You can continue other methods for one week because it takes about 5-7 days to noticed the effects of TESTOPEL. Women with vaginal dryness may need an estrogen vaginal cream.

5. What are the risks and possible side effects?

Several clinical trials have reported no serious adverse effects. Possible side effects include oily skin, acne, or increased hair growth. These effects are reversible once the pellet wears off. Some methods of testosterone can increase hemoglobin or cholesterol levels, which could increase the risk for clotting or a cardiac event. TESTOPEL should not have this effect because it is not metabolized by the liver. However, we want to monitor the effects and have you follow up in 4 weeks to re check labs and discuss your response to therapy.


The procedure is simple and takes less than 10 minutes in the office. You will lay on your side and an ice pack will be applied to the site to reduce bleeding and bruising. Next, an anesthetic is injected under the skin. A tiny incision is made (about 3 mm) and an instrument is used to place the pellet under the skin. Pressure is applied and steri strips are placed on the incision to keep it closed.


  • Place an ice pack to the incision site for 15 minutes when you get home. Repeat at bedtime and as needed. This will decreased bruising and discomfort.
  • You can resume normal activities, but avoid vigorous activity because the pellet could work its way out. If the pellet comes out will need another one placed.
  • You can shower, but do not soak the dressing in water.
  • Remove the dressing in 2-3 days and apply a steri-strip or Band-Aid if needed.
  • Remember – it is not uncommon to have bruising or tenderness. Don’t forget to use an ice pack at home!

You will follow up in 4 weeks to discuss your response to TESTOPEL and have fasting labs drawn. Do not eat or drink after midnight and do not use other forms of testosterone for at least 48 hours prior to your lab draw.